Conolidine - An Overview
Our profiling and comparison of the steps of conolidine and cannabidiol with identified pharmacological brokers predicted a MOA shared with Cav2.2 channel blocker, ω-conotoxin CVIE.2020). ACKR3 functions like a 'scavenger' that 'traps' the secreted opioids and stops them from binding on the classical receptors, thereby dampening their analgesic ex